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Other common symptoms include: Post-exertional malaise: Feeling worse after physical activity, often the next day Unrefreshing sleep: Waking up feeling unrefreshed, despite getting enough sleep Cognitive difficulties: Trouble concentrating and multi-tasking Orthostatic intolerance: Feeling lightheaded or experiencing a rapid heartbeat when standing up CFS/ME often involves cycles of flare-ups and remissions, with good days and bad days

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The "Research Use Only" Gray Market: Illegal When the 2023 restrictions hit, a massive unregulated gray market filled the gap