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Lawson JA, Farhood A, Hopper RD, Bajt ML, Jaeschke H

Nature 2023, 622: 383-392

Reintegrare i livelli di glutatione pu quindi AIUTARE IL FEGATO A RIPRENDERE LA SUA NORMALE FUNZIONE

Wound-induced systemic defense signaling requires the involvement of GLR ion channel proteins, such as GLR3.3 and GLR3.6

Details for respirometry experiments are described in Supplemental Methods

Upon activation of cell death induced by hepatic stimuli, IL-1 family cytokines released by dying liver cells stimulate the recruitment of immune cells, which in turn affect inflammation and subsequent liver damage