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A D-dopachrome converting enzyme was first discovered in mammals (Orlow et al., 1994), which associates with tyrosinase and other enzymes in the pathway to form a melanogenic complex

Additionally, IL-4-induced Arg1 expression was further upregulated by choline deprivation and Lico E treatment, reinforcing the hypothesis that CTL1 inhibition fosters a neuroprotective anti-inflammatory phenotype promoting A degradation ( The role of choline metabolism in inflammation extends beyond microglia

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