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These two characteristics of SLC7A11, namely its dispensability in normal physiology and its high expression in cancers, suggest that targeting SLC7A11 likely can selectively kill tumor cells and impair tumor growth while sparing normal cells or tissues, therefore nominating SLC7A11 as a promising therapeutic target in cancer treatment

Malagn-Rojas , Elaheh Malakan Rad , Ahmad Azam Malik , Tauqeer Hussain Mallhi , Yosef Manla , Ali Mansour , Borhan Mansouri , Mohammad Ali Mansournia , Lorenzo Giovanni Mantovani , Abdoljalal Marjani , Carlos Alberto Marrugo Arnedo , Ramon Martinez-Piedra , Adolfo Martinez-Valle , Santi Martini , Francisco Rogerlndio Martins-Melo , Miquel Martorell , Sahar Masoudi , Elezebeth Mathews , Alexander G

doi: 10.1016/j.etap.2016.07.010 54

In vivo xenobiotics like 2,4-D can undergo biotransformation in the liver, resulting in metabolites with different biological activities, including potentially endocrine-disrupting ones, not detected in the original compound during YES/YAS testing 81

Infrared therapy was administered using an infrared light therapy device with a 640 nm wavelength emission