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Mechanistically, apoptosis is initiated through two primary pathways: the intrinsic and extrinsic pathways [76]

In summary, the clinical overlap between PCOS and AITD, along with the evidence of immune system dysregulation and thyroid dysfunction in PCOS patients, underscores the importance of considering thyroid health in the management of PCOS

Additionally, probiotics (e.g., Lactobacillus rhamnosus) and prebiotics (fructooligosaccharides) regulate gut microbiota, reducing LPS translocation and Kupffer cell activation to alleviate liver injury [82]

Qualifications and Experience of Practitioners Ensure that the clinic employs qualified and experienced practitioners

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After centrifugation (20,627 g for 10 minutes, 4C) to induce phase separation, the aqueous layer was extracted and placed in a separate microfuge tube