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Cancer Res 66 : 134142

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It is important to note that, in CVDs, there is a complex interplay between different cells which must be considered

Mammalian IgG expression can be performed to ensure that the produced antibodies comprise modified (e.g., glycosylated) properties of the mammalian proteins and/or to ensure that the antibody preparation is free of endotoxins and/or other contaminants that may be present in the protein preparation from the bacterial expression system

Of note, colorectal cancer patients present a microbiota with diminished representativeness of butyrate-producing bacteria (65)