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Funding This work was partially supported by the National Natural Science Foundation of China (grant no

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In patients with chronic hepatitis B-related liver disease, changes in the abundance of specific genera are tightly linked to fibrosis stages

Protein Kinases Modulation Protein kinases such as ERK, AMPK, GSK3, p38 MAPK, and PI3K/AKT can mediate Nrf2 phosphorylation which enhance Nrf2 stability, thereby promoting nuclear Nrf2 translocation and transactivation activity (Nguyen et al., 2003