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Description

Lithium can lower the expression of MMP-9, increase the activity of Wnt/-catenin signaling, and preserve the integrity of the BBB by raising the TJ protein levels (Claudin-5 and ZO-1) [145]

Between 1990 and 2021, the number of HFPG-related CVD deaths increased more than doubled globally (from 1.02 million to 2.21 million), with mortality rates rising from 19.03 to 28.04 per 100,000 population

Avatefi et al., 2024

endoplasmic reticulum (ER)

In PD, mutations in GBA, ATP13A2, and PARK9 impair lysosomal function, leading to -synuclein accumulation and cellular toxicity (Behl et al., 2022

In particular, the mechanism underlying hypoglycemic capacity of Se-polysaccharides is discussed, and the relationship between hypoglycemic activity and chemical structure is analyzed