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As the bodys main intracellular thiol antioxidant , glutathione neutralizes reactive oxygen species and participates in cellular detoxification pathways (for example as a cofactor for glutathione peroxidase and in conjugation reactions) [5] [6]

Figure 3 Moreover, human unfertilized eggs (plasma membrane and zona pellucida) and pre-implantation embryos express CD55/DAF and CD59, preventing them from complement attack ( Figure 3 ) (304306)

Metastatic or primary lung tumours were shown to rely on enhanced expression of NFS1 to maintain the supply of FeS clusters as co-factors of multiple essential proteins and enzymes in the cell that are exposed to (damaging) high oxygen concentrations

doi: 10.1016/S0015-0282(02)03294-6 61 SalehRAAgarwalAKandiraliESharmaRKThomasAJJr.NadaEAet al

Molecular mechanism of oxidation-induced TDP-43 RRM1 aggregation and loss of function

Dalaklioglu et al., 2013