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In pancreatic cancer cells, oncogenic K-Ras maintains the nucleotide pool via the MAPK-dependent signaling pathway, leading to MYC upregulation, and the use of MEK inhibitors reduces the incorporation of glutamine-derived nitrogen into purine nucleotides 38

This review systematically unravels the intricate interplay between copper metabolism and cuproptosis, a unique copper-dependent RCD pathway, in the onset and progression of cardiovascular diseases

2022 Feb 23;10(1):e0099121

By integrating these design considerations, hydrogels can transition from passive biomaterials to dynamic, multifunctional platforms, directly addressing the limitations of conventional brachytherapy and establishing a foundation for next-generation, tumor-selective cervical cancer treatments

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Astaxanthin for heart health Multiple studies have shown the beneficial effects of astaxanthin supplementation on cardiovascular health