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After obtaining favorable results in the investigator-initiated Phase III trial JETALS, and following consultation with Tokushima University, Eisai submitted a new drug application for the treatment of ALS in Japan in January 2024, leading to its approval in September, 2024 and leading to the launch today

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Higher doses produce higher trough levels, the lowest point of drug concentration between injections

If treating a B12 deficiency, you may need weekly shots for a month, then monthly maintenance

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