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This can be attributed to local tissue hypoxia, bacterial colonisation of the wound, repetitive ischemia-reperfusion injury, and an altered cellular and systemic stress response in patients of older ages, all of which result in altered immune responses [41]

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While I do find it rather curious that there does seem to be a lot of studies that show associations, especially the most recent one, I think it's worth remembering there are also studies showing no real association, and all of these data sets have different limitations that don't account for or cannot account for factors that are very important

Effects on hair Hair shedding is another common concern

The diagnosis is based on the ultrasound, but it needs to be confirmed by cholangio-MRI [72]

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