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This review delves into the intricacies of these interactions, particularly in the context of stroke, diabetes, and systemic inflammation (Figure 2)

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Studies were selected based on methodological rigor, clinical relevance, and mechanistic insights into protective effects (antioxidant, anti-inflammatory, anticancer) and risks (organ toxicity, pro-oxidant activity, drug interactions)

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2016;5(10):e1216290

We hypothesized that the elevated levels of SP following DSS administration may reflect the organism's self-regulatory and self-defensive mechanism in response to adverse conditions