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118,119 Furthermore, SIRT1 negatively regulates the NLRP3 inflammasome, suppressing pyroptosis and protecting hepatocytes from excessive immune-mediated damage

Treatment of cells Standard reference material of PM(2.5) (catalog number: SRM2786) from NIST (Gaithersburg, USA) was used in this study 16

I.et al (2018)

In contrast, SCFAs (e.g., butyrate and propionate), which are derived from microbial fermentation of dietary fiber, exert protective effects by reducing inflammation and supporting EC integrity [190, 191]