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7B, C), indicating their irrelevance to the 5hmC changes induced by DMF

2b,e and Supplementary Table 1)

Considering an estimated average blood volume of approximately 7%8% of body weight in mice ( in vitro IC50 of 613 M for hepatocytes, taking into account the rapid distribution and metabolism occurring in vivo

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When an equimolar concentration of Cu(II) was added to the equimolar mixture of normal 2M and HSA, almost all copper was eluted in a single peak corresponding to CuHSA, demonstrating that 2M cannot compete for Cu(II) ions with HSA even at equimolar concentration (Fig