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Liu, T., Liu, Y., Zhao, X., Zhang, L., Wang, W., Bai, D.,

Relief of ovalbumin-induced airway remodeling by the glycyl-l-histidyl-l-lysine-Cu(2+) tripeptide complex via activation of SIRT1 in airway epithelial cells

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Further analysis confirmed that FOXO4-positive cells co-expressed Leydig cell markers, specifically StAR and CYP11A1, indicating that FOXO4 is indeed expressed in human Leydig cells [1]

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Activation of the Nrf2/HO-1 signaling pathway can effectively protect kidney structure from destruction, while various factors lead to the elevated activity of Nrf2/HO-1, such as the expression level of miR145-5p which directly targets Sirt5 (Mahmoud et al., 2018