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In contrast to the secretion and mRNA expression of t-PA, the secretion and gene expression of type 1 plasminogen activation inhibitor in human endothelial and smooth muscle cells is enhanced by homocysteine (Midorikawa et al, 2000)

Loguercio, C., Federico, A., Trappoliere, M., Tuccillo, C., Sio, I

Tang, Foam cells in atherosclerosis, Clin

This significant decline was reversed upon treating the rats with either manuka honey (2.5 gm/kg) or ranitidine (30 mg/kg) resulting in a significant increase of gastric mucosal GSH content (~250%) as compared to ulcer control group ( P = 0.000) (Figure 5)

Variability in plant origin, harvesting conditions, and extraction methods can significantly alter phytochemical profiles, underscoring the importance of standardized manufacturing practices for clinical and translational applications (6)

Cross-strand disulfides in the non-hydrogen bonding site of antiparallel -sheet (aCSDns): poised for biological switching