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Additionally, the presence of amyloid beta in the striatum of APP-NLGF mice (containing the Swedish KM670/671NL mutation, the Iberian I716F mutation and the Artic E693G mutation) is inversely correlated with motivational levels (Hamaguchi et al., 2019)

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Intolerances and allergies can also occur

The absence of universally accepted reference ranges and calibration standards further complicates cross-study comparisons and limits the translation of these biomarkers into routine clinical practice

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