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To compare the groups, we used 2-tailed Students t test or 1-way ANOVA, followed by Tukeys or Dunnetts post hoc test

Mice were also intraperitoneally treated with 3 mg/kg bazedoxifene acetate (BZA) (MedchemExpress) or 10 mg/kg testosterone enanthate (TTE) (Fujifilm) dissolved in 100 l of corn oil, and 1 mg/kg GSK'074 (MedchemExpress), 2 mg/kg MitoQ (Selleck) dissolved in 100 l of 10% methylcellulose (Fujifilm) containing 0.01% tween-80 (Nacalai)

Many researchers have also studied the combined effects of arsenic trioxide and radiotherapy

The AuNCs catalyse the hydrogen peroxide (H 2 O 2 )-mediated oxidation of a chromogenic substrate resulting in a colour change visible to the naked eye

2.3 Dysbiosis of gut virome The human virome is predominantly composed of eukaryotic viruses (viruses that target human cells) and prokaryotic viruses (viruses that infect bacteria and archaea)

The aging process is linked to diminished synthesis and variety of IgA, along with compromised IgA binding specificity to gut bacteria, which disrupts the equilibrium between osteogenesis and osteoclastogenesis and potentially contributes to age-related OP