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Cell 127:397408 Ebrahim AS, Ko L-w, Yen S-H (2010) Reduced expression of peroxisome-proliferator activated receptor gamma coactivator-1 enhances -synuclein oligomerization and down regulates AKT/GSK3 signaling pathway in human neuronal cells that inducibly express -synuclein

This pathway is the main quantitative route for endogenous glycine production in humans and is particularly active in tissues with high metabolic rates and demands for nucleotide synthesis, such as the liver and central nervous system