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The clinical significance of externally altering these pathways can vary between medicines and diseases

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However, when the same adduct was prepared using bromo-propynamide (BYA) reagent 14 , the cross-click conjugation was also successful (see Supplementary Section 10) and the resulting conjugate was significantly more stable, as most of it survived a treatment with 100 equivalents of glutathione for several days

[106] Hannah in the Presence of the Lord, 63