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6, September: 3083-3092, 2018 Patients and Methods: This study included 30 female patients with melasma who were selected among those attending the Outpatient Clinic of Dermatology and Venereology De- partment, Tanta University Hospitals during the period between December, 2015 and February, 2017

To overcome this problem, itaconate esters with higher lipophilicity and membrane permeability such as dimethyl itaconate (DI, dimethyl 2-methylidenebutanedioate) or 4-octyl itaconate (OI, 2-methylidene-4-octoxy-4-oxobutanoic acid) are frequently used to study pharmacological effects of itaconate in vivo and in vitro [3]

[DOI] [PubMed] [Google Scholar] 95.Trkanolu A., Can Demirden B., Demirkaya ., Bek S., Adal O

Pregnancy-related medications and the effects of MTHFR also play a role in hormone imbalances

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