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This review synthesizes current knowledge on the liver-brain crosstalk in AD, emphasizing the mechanistic role of liver in bridging metabolic dysfunction with neurodegeneration and underscores the diagnostic and therapeutic potential of hepatokines in addressing ADs complex pathology

Acknowledgments The authors would like to express their sincere gratitude to Hao Wang, Cankun Zhou, Yonglian Chen, Jun Lyu, Minqing Feng, and Xiaobin Huang for their valuable contributions to the early stages of this work and for their collaborative support throughout the research process

Recovery and reconstruction of energy production and maintaining the energy balance by applying exogenous ALC as an energy source to compensate for the reduced energy in the brain of the mouse model of MS could be addressed as a therapeutic strategy

Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes

Results STBD1-mediated glycophagy plays a crucial role in energy metabolism in oysters To investigate the role of autophagy in the response of oysters to stress, we manipulated nutritional status in C

Guo X, Yin X, Liu Z, Wang J