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Eur J Clin Invest 26:3844, PMID: 8682153 Brigelius-Floh R, Banning A, Kny M, Bl G (2004) Redox events in interleukin-1 signaling

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[39] These allergic reaction-like symptoms, which typically occur within 3060 minutes of ingesting alcoholic beverages, do not appear to reflect the operation of classical IgE- or T cell-related allergen-induced reactions but rather are due, at least in large part, to the action of acetaldehyde in stimulating tissues to release histamine, the probable evoker of these symptoms

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Therefore, though market is huge, it is very difficult to have skin whitening treatment provided by clinics especially because in some countries it is sometimes ban or strickly regulated because of lack of backed reports

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