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Arginine is essentially involved in many catalytic, regulatory, and structural functions

Molecules 23:1091

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Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X

A study employing high-resolution immunocytochemistry at both light and electron microscopic levels in rodents has demonstrated that neurons efficiently uptake lactate via monocarboxylate transporter 2 (MCT2), a high-affinity transporter localized at postsynaptic densities to facilitate lactate import from astrocyte-released sources (Bergersen, 2007) and subsequently convert it to pyruvate via lactate dehydrogenase isotype 1

This comprehensive review will explore recent advancements in understanding ferroptosis mechanisms in sepsis-induced acute lung injury (ALI) and discuss the potential of targeting ferroptosis as a novel therapeutic approach, along with associated challenges