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doi: 10.1038/bmt.2008.437 26 van den AnkerJ

GAD activity, regulated by calcium (Ca 2+ ) and calmodulin (CaM), performs decarboxylation of glutamate to produce GABA

Such a large number of proteins that require zinc to fulfill their function stimulates reflection on how complex the entire zinc proteome is and how sophisticated is the mechanism by which proteins gain access to zinc ions within a cell