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The codon usage in these genes was optimized based on codon usage tables 1 (Nakamura, 2000) in a codon harmonization tool (Haupka, 2020)

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Senthong V, Wang Z, Li XS, Fan Y, Wu Y, Tang WH et al

Since red meat is particularly rich in LC [69], dietary intervention in healthy adults, indicated a significant increase in plasma and urine TMAO levels following 4 weeks of the red meat-enriched diet [70]

Essa substncia, produzida naturalmente pelo organismo a partir dos aminocidos essenciais lisina e metionina, desempenha um papel fundamental no transporte de gorduras para dentro das clulas, onde ocorre a oxidao e a consequente produo de energia