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CORTISONE INJECTIONS ARE USUALLY ONLY RECOMMENDED AS A SHORT-TERM TREATMENT While they can be very effective, too many injections of cortisone over a short period of time have been shown to cause damage to the tendons, ligaments, and cartilage at the injection site

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Clinical investigations into the cardiovascular benefits of UA remain limited, with the majority of current evidence originating from in vitro and animal models

NONSTEROIDAL ANTI-INFLAMMATORY DRUGS MECHANISM OF ACTION The nonsteroidal anti-inflammatory drugs comprise a large family of weak acidic drugs whose pharmacological effects result primarily from the inhibition of cyclooxygenase (COX) , an enzyme that catalyzes the first step in the synthesis of prostaglandins from arachidonic acid and other precursor fatty acids (see Chapter 26)