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Whether this transient nature reflects real reversibility or formation of genotoxic, depurinated sites remains to be investigated at the molecular level

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Importantly, the inhibitory effects of 5-fluorouracil exhibited higher cytotoxicity against HepG2 cells, while -cyclodextrin, K 3 (C 36 H 60 O 30 ) 2 7H 2 O, and (C 36 H 60 O 30 )H 2 O showed no cytotoxicity under the same drug concentration

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Acta 1802 , 5261 (2010)

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2009;296(6):G115166

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