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Consistent with perturbed glutathione metabolism, CLP mice exhibited significant downregulation of the Nrf2/HO-1 antioxidant axis: reduced Nrf2, a master transcriptional regulator of antioxidant genes, and its target HO-1 were reduced, indicating impaired upstream antioxidant regulation

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Combination Therapy Between Tumor Vaccine and RT The tumor vaccine has been a research hotspot in recent years

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These results indicate that VNS can effectively improve the mitochondrial morphological changes and mitigate mitochondrial damage in cardiomyocytes induced by hepatic ischemiareperfusion injury, while erastin can counteract this protective effect

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Apoptosis, DNA damage, excitotoxicity, and oxidative stress may all play a role in developing neurodegenerative diseases brought on by hyperhomocysteinemia

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In functional medicine, we always ask: whats the root cause

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