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When the desensitized GSH I-encoding gene gshA * was cloned, the activity of the mutant GSH I increased tenfold compared with the wild type enzyme

Un complment contenant du glutathion oxyd (GSSG) oblige la cellule le rduire avant de pouvoir l'utiliser, ce qui consomme des ressources (NADPH) et limite l'intrt de la supplmentation

This section reports PD data N=388 obtained between August 1, 2014 and July 31, 2015

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We also added glutathione reductase Gor (1 M) and its co-substrate NADPH+H + (250 M), to ensure the retention of the reduced state of the exogenous glutathione (see Figure 6D for a schematic overview)