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Within neonatology, although the methodological rigor of available studies is frequently limited (397, 398), emerging evidence suggests that specific probiotic strains may confer protection against necrotizing enterocolitis in preterm infants

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Concurrently, standardizing the assessment of metabolic assessments is critical: the hyperinsulinemic-euglycemic clamp should be universally prioritized as the gold standard for evaluating insulin sensitivity to minimize bias arising from methodological heterogeneity