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131 Because of its antioxidant properties, vitamin E had been proposed as a therapeutic agent, 139 , 140 , 141 but subsequent evaluation of large doses of the vitamin failed to demonstrate an ameliorative effect on anemia

In both compartments, acetate is converted into acetyl-CoA via thioesterification, consuming energy equivalent to two terminal phosphate bonds from ATP 254,255

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Wei JW, Huang K, Yang C, Kang CS

For example, OBX-115 expresses membrane-bound human IL-15 under pharmacological control to provide cell-intrinsic survival and proliferation signals and potentially reduce the need for exogenous IL-2 [109, 111]