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The altered expression, modification, and function of these transducers as TRPV1, transient receptor potential ankyrin 1 (TRPA1), and transient receptor potential melastatin 8 (TRPM8), contribute to peripheral sensitization and may play an important role in pain phenotyping

However, it should be noted that TE may have limitations in distinguishing between early fibrosis stages (F0-F1), which could influence the sensitivity of the method in some cases [54]