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Immunomodulationa general review of the current state-of-the-art and new therapeutic strategies for targeting the immune system

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For the detachment and collection of the samples, a rubber-tipped cell scraper was used

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This suggests that CD38 might be a potential additional immunotherapeutic target in HCC and NSCLC, and can be used together with PD-1/PD-L1 immunotherapy ( Reasons for Choosing CD38 as a Therapeutic Target The main reasons why CD38 has become a tumor treatment target are as follows: (1) In a hypoxic TME, CD38 acts as an extracellular enzyme to catalyze NAD + existing in the TME into ADPR or cADPR