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10.1089/jop.2013.0165 3 AmicF.DrmicD.BilicZ.KrezicI.ZizekH.PeklicM.et al (2018)

& Cavenee, W

Ethics statement Ethical review and approval was not required for the study on human participants in accordance with the local legislation and institutional requirements

It is considered a second-line treatment option when first-line treatments, such as oral medications, fail to provide adequate relief or are associated with significant side effects [102]