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Description

COX2 expression is minimal in normal physiological conditions but abundant in inflammatory cells

This means it was synthetically designed to be highly selective

ROS can attack intracellular DNA molecules, lipids, and proteins, among other substances, ultimately leading to intracellular ROS accumulation and depletion of antioxidant capacity [12]

World J Gastrointest Surg 15(4):495519 Kim J, Yoo RN, Cho HM, Kye BH, Kim HJ (2021) Adjuvant chemotherapy for patients with stage II high-risk and III colon cancer: hindering factors to adherence and impact on long-term survival