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Metformin like other AEDs such as tiagabine and vigabatrin can trigger absence seizure by increasing the availability of GABA which induces stimulation of GABA-B (Yang et al

Nickel Column Affinity Chromatography Common chelate ligands of IMAC are TED(carboxymethyl ethylenediamine), NTA(nitrilotriacetic acid) and IDA(iminodiacetic acid)