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Mukherjee C, Kling T, Russo B, Miebach K, Kess E, Schifferer M, et al

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34 It is important to note that the antioxidant properties of Mn are outcompeted by cellular iron binding to MnSOD, so iron may counteract the benefits of manganese antioxidants

When taken as a supplement, NAC boosts the production of glutathione in the body, indirectly enhancing the bodys ability to neutralize harmful free radicals and support overall detoxification

1 Introduction Acute respiratory distress syndrome (ARDS) is a severe, life-threatening inflammatory condition of the lungs commonly triggered by infections such as bacterial pneumonia, viral pathogens (e.g., influenza and SARS-CoV-2), and systemic sepsis ( The pathogenesis of ARDS involves an exaggerated immune response that damages alveolar structures, disrupts the alveolar-capillary barrier, and promotes excessive inflammation, vascular leakage, and oxygenation failure ( Regulated cell death pathways, such as apoptosis, pyroptosis, necroptosis, and ferroptosis, play pivotal roles in controlling inflammation and maintaining tissue integrity