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[76] Combined intraperitoneal administration of vitamin C (1g/kg) and vitamin K (10 mg/kg) given prior to chemotherapy increased survival and the effect of several chemotherapeutic agents (cyclophosphamide, vinblastine, doxorubicin, 5-fluorouracil, procarbazine, and asparaginase) in a murine ascitic liver tumor model

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Figure 3c shows that surface-targeted LaccID enriches N-cadherin but not calreticulin, while surface-targeted APEX2 and HRP enrich both markers because of (1) substantial pools of APEX2 and HRP in the ER lumen because of their imperfect targeting to the cell surface, and (2) high activity of APEX2 and HRP in the ER compartment