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10.1177/09603271211002883 61 KarvanS.SadeghiA.FarrokhiP.NekoueeA.SharifiM.MoghaddasA

Drazic A, Miura H, Peschek J, Le Y, Bach NC, Kriehuber T, Winter J (2013) Methionine oxidation activates a transcription factor in response to oxidative stress

In addition, they can also inhibit inflammation and oxidant-induced programmed cell death (e.g., apoptosis, necroptosis, pyroptosis) [64, 66, 67]

Another example for the role of GM on drugs metabolism is patients harboring high levels of the GM metabolite, p-Cresol who were found to be more liable to acetaminophen-induced hepatotoxicity as p-Cresol competes with acetaminophen for hepatic sulfonation during phase II of drug metabolism [34]

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