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Bilayer self assembly encapsulated by engineered vesicle disrupts glutathione to induce Disulfidptosis enhanced cuproptosis for tumor immunotherapy ScienceDirect Glutathione depleting mitochondria targeting nanodrugs for stress amplification and immune activation via synergistic photodynamic therapy and cuproptosis ScienceDirect Schematic illustration indicates the mechanism of cuproptosis induction Download Scientific Diagram Cuproptosis mechanism in cancer! As a copper dependent regulated form of cell death, cuproptosis is critically important for developing targeted cancer therapies and overcoming drug resistance. A multidimensional framework deciphers the physiological Cuproptosis: lipoylated TCA cycle proteins mediated novel cell death pathway Signal Transduction and Targeted Therapy Frontiers Cuproptosis: potential new direction in diabetes research and treatment
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