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In contrast to the Sec pathway which translocates unfolded proteins, the Tat pathway translocates already folded proteins through a cellular membrane

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Aquilariae Lignum fraction pretreatment of LPS-stimulated BV2 microglia cells significantly reduced NO, cyclooxygenase-2 (COX-2), IL-1, and prostaglandin E2 levels and attenuated nuclear factor-kappaB (NF-B) and p65 activities [109]

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doi: 10.3389/fmolb.2021.765970 Received 27 August 2021 Accepted 01 November 2021 Published 22 November 2021 Volume 8 - 2021 Edited by Marc Diederich, Seoul National University, South Korea Reviewed by Dan Herschlag, Stanford University, United States Adrian Drazic, University of Bergen, Norway Updates Copyright 2021 Mannervik, Ismail, Lindstrm, Sjdin and Ing

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