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doi: 10.1212/01.WNL.0000152046.11390.45 23

Does nitric oxide modulate mitochondrial energy generation and apoptosis

Li, Y., Li, D., Yang, Y

Hepatocyte growth factor (HGF) and stem cell factor (SCF) maintained the stemness of human bone marrow mesenchymal stem cells (hBMSCs) during long-term expansion by preserving mitochondrial function via the PI3K/AKT, ERK1/2, and STAT3 signaling pathways

Colon biopsies performed on PD patients showed accumulation of -synuclein in the colons enteric neurons before diagnosis of motor symptoms, which suggests -synuclein may aggregate in the ENS before its dissemination to the brain (56)

435 We look forward to subsequent translational studies to identify specific baseline or post-treatment biomarkers that may more accurately predict subgroups sensitive to olaparib therapy