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published as US 20070053970

Whereas, GA (Group IV) pretreatment significantly prevented ISO-induced overexpression of TNF-, IL-6, NF-B, COX-2 and iNOS in rat cardiac tissue (Figure 5A,B)

Rapamycin prevents early steps of the development of diabetic nephropathy in rats

Clinically, DCD manifests as acquired cognitive and behavioral deficits that impair patients self-management capacity and treatment adherence, further accelerating disease progression (126)