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In addition to markers of protein oxidative damage, 8-oxo-dG, a marker of DNA oxidative damage, was significantly elevated in both cerebellum and BA22 from the autism cases relative to controls

Inhibition of mitochondrial electron transport by peroxynitrite

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Several studies have shown that prophylactically lithium can reduce manic relapses, even if its efficacy is significantly lower in the reduction of depressive relapses 18