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WO2019239340A1 - Reduced glutathione in a highly soluble, amorphous solid form, and process for the preparation thereof - Google Patents Reduced glutathione in a highly soluble, amorphous solid form, and process for the preparation thereof Download PDF Info Publication number WO2019239340A1 WO2019239340A1 PCT/IB2019/054906 IB2019054906W WO2019239340A1 WO 2019239340 A1 WO2019239340 A1 WO 2019239340A1 IB 2019054906 W IB2019054906 W IB 2019054906W WO 2019239340 A1 WO2019239340 A1 WO 2019239340A1 Authority WO WIPO (PCT) Prior art keywords glutathione reduced glutathione sodium salt product aqueous solution Prior art date Legal status (The legal status is an assumption and is not a legal conclusion

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These findings suggested that DMB may act through inhibiting NF-B signaling pathway to inhibit the inflammation in intestine and alleviate UC development

283,284,285 PEG modification can inhibit the binding of apolipoprotein E to LNPs, a key mechanism for LNP uptake by the liver, thereby affecting liver uptake of LNPs