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Ornelas et al, 2017)

10.3390/ijms232314828 3 AlyoshinaN

We assessed the efficacy of SDUY-225 to inhibit TRPM7 channel activity in whole-cell patch-clamp experiments conducted with HEK293 cells overexpressing TRPM7[49]

Collectively, these mechanisms illustrate how PICs and glial cells polarization regulate central sensitization through modulation of synaptic plasticity