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Moreover, cholinergic system deficits in AD patients, such as reduced activity of acetylcholinesterase and choline acetyltransferase, impaired synthesis and release of acetylcholine, huperzine A (Hup A), a highly selective acetylcholinesterase inhibitor, are commonly used to treat memory impairment, cognitive dysfunction, and mood and behavioral disorders associated with AD

57 HT-1080 N cells were seeded in a 6-well dish such that each well contained 50,000 cells (day 0)

doi: 10.1016/j.immuni.2009.01.009 103 FiresteinGSMcInnesIB

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