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Proteasomal dysfunction is believed to play a role in the pathogenesis of PD because ubiquitin builds up in LBs and interacts with the proteasomal system through interactions with parkin and UCH-L1

Int J Mol Sci (2019) 21(1):55

Nucleic Acids Res 40 , e130 (2012)

Nieto MA, Huang RY-J, Jackson RA, Thiery JP

The authors concluded that the anti-inflammatory effect of the KD in the glaucomatous retina is dependent on its ability to restore normal ATP production through the supply of ketone bodies and consequential changes in AMPK activation

Regulation of IGF binding protein-1 in hep G2 cells by cytokines and reactive oxygen species